Cancer remains one of the deadliest diseases worldwide, affecting millions of people every year. The conventional treatments for cancer, such as chemotherapy, radiation therapy, and surgery, often come with side effects and limitations. As a result, there is a growing interest in complementary and alternative therapies, including the use of medicinal mushrooms. Among the many types of mushrooms known for their potential health benefits, Turkey Tail Mushroom (scientifically known as Trametes versicolor) stands out for its properties against cancer cells.
Turkey Tail Mushroom, also known as Yun Zhi in Chinese medicine and Kawaratake in Japanese, is a type of mushroom that belongs to the Polyporaceae family. It is a wood-decaying fungus commonly found in forests around the world, including North America, Europe, Asia, and Australia. Its distinctive fan-shaped cap with concentric rings and vibrant colors resembling a turkey’s tail gives it its name. While it is not edible due to its tough texture, Turkey Tail Mushroom has been used for centuries in traditional Chinese and Japanese medicine for its potential health benefits, including its anti-cancer properties.
Turkey Tail Mushroom contains various bioactive compounds that are believed to contribute to its anti-cancer properties. One of the key components is beta-glucans, which are complex carbohydrates known for their immune-boosting effects. Beta-glucans stimulate the immune system by activating immune cells, such as natural killer cells and macrophages, which play a crucial role in detecting and destroying cancer cells. Turkey Tail Mushroom also contains other compounds, such as polysaccharides, triterpenoids, phenols, and flavonoids, which have been shown to have anti-cancer effects in preclinical studies.
Numerous studies have investigated the anti-cancer properties of Turkey Tail Mushroom and its potential for inhibiting cancer cell growth. Research has shown that Turkey Tail Mushroom extract can inhibit the growth of various types of cancer cells, including breast, prostate, lung, liver, colon, and stomach cancers, among others. In a study published in the journal “Cancer Immunology, Immunotherapy” in 2012, researchers found that the polysaccharopeptide (PSP) extracted from Turkey Tail Mushroom significantly suppressed the growth of breast cancer cells by inducing apoptosis, a process of programmed cell death, and inhibiting cancer cell proliferation.

In addition to its direct anti-cancer effects, Turkey Tail Mushroom has also been shown to boost the immune system, which plays a critical role in cancer prevention and treatment. The immune system is responsible for identifying and destroying abnormal cells, including cancer cells, and preventing their growth and spread. Studies have shown that Turkey Tail Mushroom can enhance the activity of immune cells, such as natural killer cells, which can recognize and destroy cancer cells. A clinical study published in the journal “Integrative Cancer Therapies” in 2014 found that Turkey Tail Mushroom extract increased the immune function of breast cancer patients undergoing chemotherapy, suggesting that it may have potential as an adjunct therapy in cancer treatment.
Furthermore, Turkey Tail Mushroom has been shown to have anti-inflammatory properties, which can be beneficial in cancer treatment. Chronic inflammation has been linked to the development and progression of cancer, as it can promote DNA damage, cell mutation, and tumor growth. Turkey Tail Mushroom contains compounds, such as phenols and flavonoids, that possess anti-inflammatory properties and can help reduce inflammation in the body. In a study published in the journal “Food and Chemical Toxicology” in 2013, researchers found that Turkey Tail Mushroom extract reduced inflammation and oxidative stress in colon cancer cells, suggesting its potential as an anti-inflammatory agent in cancer prevention and treatment.

Here are some ways to use Turkey Tail Mushroom to help kill cancer cells:
- Turkey Tail Mushroom Extract: Turkey Tail Mushroom is available in various forms, including capsules, powders, and extracts. Turkey Tail Mushroom extract, which is rich in bioactive compounds, such as beta-glucans and polysaccharopeptides (PSP), is commonly used for its potential anti-cancer properties. The recommended dosage and frequency of Turkey Tail Mushroom extract may vary depending on the specific product and individual health conditions, so it’s important to follow the instructions provided by the manufacturer or consult with a healthcare professional for appropriate dosing.
- Tea or Decoction: Turkey Tail Mushroom can also be brewed into a tea or decoction, which is a concentrated liquid extract obtained by boiling the mushroom in water. To make Turkey Tail Mushroom tea, simply simmer dried or fresh Turkey Tail Mushroom in water for about 30 minutes to an hour, then strain the liquid and drink it as a tea. You can add other beneficial herbs, such as ginger or ginseng, to enhance the flavor and potential health benefits of the tea.
- Powdered Form: Turkey Tail Mushroom is also available in powdered form, which can be added to food or beverages. You can mix Turkey Tail Mushroom powder into smoothies, soups, or sauces to incorporate it into your daily diet. However, it’s important to note that the quality and potency of Turkey Tail Mushroom powder may vary among different brands, so choose a reputable source and follow the recommended dosage instructions.
- Immune-Boosting Supplements: Turkey Tail Mushroom is known for its immune-boosting properties, which can help strengthen the body’s natural defenses against cancer cells. Some Turkey Tail Mushroom supplements are formulated with other immune-boosting herbs, such as reishi or astragalus, to further enhance their potential benefits. These supplements are available in various forms, such as capsules or tablets, and can be taken as part of a comprehensive immune-boosting regimen under the guidance of a healthcare professional.
- Adjuvant Therapy: Turkey Tail Mushroom may also be used as an adjuvant therapy, which is a complementary treatment used alongside conventional cancer treatments, such as chemotherapy or radiation therapy. Some studies have shown that Turkey Tail Mushroom extract can enhance the effectiveness of chemotherapy or radiation therapy by increasing immune function, reducing inflammation, and inhibiting cancer cell growth. However, it’s important to note that the use of Turkey Tail Mushroom or any other natural remedy as an adjuvant therapy should be discussed with a healthcare professional to ensure safety and effectiveness.
- Topical Application: In some cases, Turkey Tail Mushroom extract can also be applied topically for skin cancers or other skin conditions. Turkey Tail Mushroom creams or ointments may be available for topical use, and they can be applied directly to the affected area as directed by a healthcare professional.
It’s important to note that while Turkey Tail Mushroom has shown promising results in preclinical and clinical studies for its potential anti-cancer properties, it’s always essential to consult with a qualified healthcare professional before starting any new supplement or natural remedy, especially if you are undergoing cancer treatment or have any underlying health conditions. A healthcare professional can help determine the appropriate dosage, frequency, and duration of Turkey Tail Mushroom use based on your individual health needs and provide comprehensive care tailored to your specific condition.